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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927074Generated: November 1, 2026

1-Ethynyl-2,4-difluorobenzene → 3,4-bis(Benzyloxy)-6-[(2,4-difluorophenyl)ethynyl]pyridazine

https://huagongshe.com/reaction/927074

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Ethynyl-2,4-difluorobenzeneHCID 5063820—
Reactant3,4-Bis(benzyloxy)-6-chloropyridazineHCID 12213474—
Reactant3,4-Bis(benzyloxy)-6-(phenylethynyl)pyridazineHCID 71270419—
Product3,4-bis(Benzyloxy)-6-[(2,4-difluorophenyl)ethynyl]pyridazineHCID 71270040—

Reaction Steps

Prepared as described for 3,4-bis(benzyloxy)-6-(phenylethynyl)pyridazine (Intermediate 2) from 3,4-bis(benzyloxy)-6-chloropyridazine (Intermediate 1) and 1-ethynyl-2,4-difluorobenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290456B2
Source datasetuspto-grants-2016_03
ORD IDord-cac5c0beb5df4bff80f0dfaa20950f59
Source noteuspto-grants-2016_03