HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoro-4-iodotoluene → HCID 71270242, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoro-4-iodotoluene | HCID 123492 | — |
| Reactant | 3,4-Bis(benzyloxy)-6-{[5-(trifluoromethyl)pyridin-2-yl]ethynyl}pyridazine | HCID 71269910 | — |
| Reactant | 3,4-Bis(benzyloxy)-6-ethynylpyridazine | HCID 86677025 | — |
| Product | HCID 71270242 | HCID 71270242 | 67% |
Reaction Steps
Prepared as described for 3,4-bis(benzyloxy)-6-{[5-(trifluoromethyl)pyridin-2-yl]ethynyl}pyridazine (Intermediate 6) from 3,4-bis(benzyloxy)-6-ethynylpyridazine (Intermediate 5) and 2-fluoro-4-iodo-1-methylbenzene in 67% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290456B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-db41ad2c887c4deb8b16ab8888e69c05 |
| Source note | uspto-grants-2016_03 |