Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927092Generated: October 27, 2026

1-Ethynyl-2-(trifluoromethyl)benzene → 3,4-Bis(benzyloxy)-6-((2-trifluoromethylphenyl)ethynyl)pyridazine

https://huagongshe.com/reaction/927092

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Ethynyl-2-(trifluoromethyl)benzeneHCID 4100856—
Reactant3,4-Bis(benzyloxy)-6-chloropyridazineHCID 12213474—
Reactant3,4-Bis(benzyloxy)-6-(phenylethynyl)pyridazineHCID 71270419—
Product3,4-Bis(benzyloxy)-6-((2-trifluoromethylphenyl)ethynyl)pyridazineHCID 71270351—

Reaction Steps

Prepared as described for 3,4-bis(benzyloxy)-6-(phenylethynyl)pyridazine (Intermediate 2) from 3,4-bis(benzyloxy)-6-chloropyridazine (Intermediate 1) and 1-ethynyl-2-(trifluoromethyl)benzene in quantitative yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290456B2
Source datasetuspto-grants-2016_03
ORD IDord-d886786e1ee34d698b47e20bfef0efb9
Source noteuspto-grants-2016_03