(Cyclohexylmethyl)(methyl)amine → HCID 71270177, 화합물

HRID 927098노트

반응식

HRID 927098 반응식
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([NH:23][CH2:24][C:25]2[CH:30]=[CH:29][C:28](F)=[CH:27][CH:26]=2)[N:12]=[N:13][C:14]=1[O:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:32](OC1N=NC(Cl)=CC=1OCC1C=CC=CC=1)C1C=CC=CC=1.C1(CNC)CCCCC1>>[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([N:23]([CH2:24][CH:25]2[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]2)[CH3:32])[N:12]=[N:13][C:14]=1[O:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

4

반응물 3

HCID 117276(Cyclohexylmethyl)(methyl)amineHCID 122134743,4-Bis(benzyloxy)-6-chloropyridazine2회HCID 712699075,6-bis(Benzyloxy)-N-[(4-fluorophenyl)methyl]pyridazin-3-amine2회

생성물 1

HCID 71270177HCID 71270177, 화합물수율 26%

실험 절차

Prepared as described for 5,6-bis(benzyloxy)-N-[(4-fluorophenyl)methyl]pyridazin-3-amine (Intermediate 45) from 3,4-bis(benzyloxy)-6-chloropyridazine (Intermediate 1) and 1-cyclohexyl-N-methylmethanamine in 26% yield.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-131f5230535f476d854e88626e4e3d5c
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09290456B2

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