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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927100Generated: November 2, 2026

3,4-Bis(benzyloxy)-6-chloropyridazine → 3,4-bis(Benzyloxy)-6-[(4-chlorophenyl)methyl]pyridazine

https://huagongshe.com/reaction/927100

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-Bis(benzyloxy)-6-chloropyridazineHCID 12213474—
Reactant3,4-bis(Benzyloxy)-6-[(3-chlorophenyl)methyl]pyridazineHCID 71270271—
ReactantHCID 178478120HCID 178478120—
Product3,4-bis(Benzyloxy)-6-[(4-chlorophenyl)methyl]pyridazineHCID 7127020295%

Reaction Steps

Prepared as described for 3,4-bis(benzyloxy)-6-[(3-chlorophenyl)methyl]pyridazine (Intermediate 48) from 3,4-bis(benzyloxy)-6-chloropyridazine (Intermediate 1) and (4-chlorobenzyl)zinc(II) chloride in 95% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290456B2
Source datasetuspto-grants-2016_03
ORD IDord-59756e2fccbb46e89eb0bf1ef2911d79
Source noteuspto-grants-2016_03