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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927118Generated: October 25, 2026

1-Bromo-2-chloro-4-(trifluoromethyl)benzene → HCID 71270172, compound

https://huagongshe.com/reaction/927118

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-2-chloro-4-(trifluoromethyl)benzeneHCID 14273266—
Reactant3,4-Bis(benzyloxy)-6-((3-methyl-4-(trifluoromethyl)phenyl)-ethynyl)pyridazineHCID 71269897—
Reactant3,4-Bis(benzyloxy)-6-ethynylpyridazineHCID 86677025—
ProductHCID 71270172HCID 7127017275%

Reaction Steps

Prepared as described for 3,4-bis(benzyloxy)-6-((3-methyl-4-(trifluoromethyl)phenyl)-ethynyl)pyridazine (Intermediate 74) from 3,4-bis(benzyloxy)-6-ethynylpyridazine (Intermediate 5) and 1-bromo-2-chloro-4-(trifluoromethyl)benzene in 75% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290456B2
Source datasetuspto-grants-2016_03
ORD IDord-44c5a00258744fd9acd618277f33b5d8
Source noteuspto-grants-2016_03