HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → HCID 178424566, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 3,4-Bis(benzyloxy)-6-[2-(4-fluoro-3-methylphenyl)ethynyl]pyridazine | HCID 71270369 | — |
| Reactant | 3-Hydroxy-6-(2-Phenylethyl)pyridazin-4(1h)-One | HCID 178518808 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178424566 | HCID 178424566 | — |
Reaction Steps
Prepared by the same method as for 4-hydroxy-6-(2-phenylethyl)pyridazin-3(2H)-one (Example 1) from 3,4-bis(benzyloxy)-6-[2-(4-fluoro-3-methylphenyl)ethynyl]pyridazine (Intermediate 29) except that the solvent mixture used for the hydrogenation was made up of ethyl acetate and methanol (1:1) and the final material was recrystallised from ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290456B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-2b934151f75d4befb6839552acdcb1c9 |
| Source note | uspto-grants-2016_03 |