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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927333Generated: November 1, 2026

6-(4-Chlorophenyl)picolinic acid → 6-(4-Chloro-phenyl)-pyridine-2-carboxylic acid [1-methyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethyl]-amide

https://huagongshe.com/reaction/927333

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(4-Chlorophenyl)picolinic acidHCID 24730136—
Reactant2-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-2-amineHCID 43559251—
Product6-(4-Chloro-phenyl)-pyridine-2-carboxylic acid [1-methyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethyl]-amideHCID 71093569—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 6-(4-chlorophenyl)-2-pyridinecarboxylic acid (CAN 135432-77-8) and α,α,5-trimethyl-1,2,4-oxadiazole-3-methanamine (CAN 1153831-97-0) as starting materials, MS (LC/MS): 357.1 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290451B2
Source datasetuspto-grants-2016_03
ORD IDord-2df8a89e5d0949feb9f178cbba1ae695
Source noteuspto-grants-2016_03