Methyl 2-amino-2-methylpropanoate → HCID 71087928, compound

HRID 927341Notes

Reaction equation

HRID 927341 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[NH:9][C:10]1[N:15]=[C:14]([C:16]([OH:18])=O)[CH:13]=[CH:12][C:11]=1[CH3:19].[CH3:20][O:21][C:22](=[O:27])[C:23]([CH3:26])([CH3:25])[NH2:24]>>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[NH:9][C:10]1[N:15]=[C:14]([C:16]([NH:24][C:23]([CH3:26])([CH3:25])[C:22]([O:21][CH3:20])=[O:27])=[O:18])[CH:13]=[CH:12][C:11]=1[CH3:19]

Participants

3

Reactant 2

HCID 4186341Methyl 2-amino-2-methylpropanoateHCID 71087937HCID 71087937, compound

Product 1

HCID 71087928HCID 71087928, compound

Procedure

The title compound was synthesized in analogy to Example 4 b, using 6-(2,4-dichloro-phenylamino)-5-methyl-pyridine-2-carboxylic acid and 2-methyl-alanine methyl ester as starting materials, MS (EI): m/e 396.0 [M+H]+.

Sources & evidence

ORD record
ord-0ed725dd80534e93964ffcf64eb1ff7c
Source dataset
uspto-grants-2016_03
Patent number
US09290451B2

Reaction notes

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