Methyl 2-amino-2-methylpropanoate → 2-{[6-Cyclopropylmethoxy-5-(tetrahydro-pyran-4-yl)-pyridine-2-carbonyl]-amino}-2-methyl-propionic acid methyl ester
反応式
[CH:1]1([CH2:4][O:5][C:6]2[N:11]=[C:10]([C:12]([OH:14])=O)[CH:9]=[CH:8][C:7]=2[CH:15]2[CH2:20][CH2:19][O:18][CH2:17][CH2:16]2)[CH2:3][CH2:2]1.[CH3:21][O:22][C:23](=[O:28])[C:24]([CH3:27])([CH3:26])[NH2:25]>>[CH3:21][O:22][C:23](=[O:28])[C:24]([NH:25][C:12]([C:10]1[CH:9]=[CH:8][C:7]([CH:15]2[CH2:20][CH2:19][O:18][CH2:17][CH2:16]2)=[C:6]([O:5][CH2:4][CH:1]2[CH2:2][CH2:3]2)[N:11]=1)=[O:14])([CH3:27])[CH3:26]参加物
3
実験手順
The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-(tetrahydro-pyran-4-yl)-pyridine-2-carboxylic acid and 2-methyl-alanine methyl ester as starting materials, MS (EI): m/e 377.2 [M+H]+.
出典と根拠
- ORDレコード
- ord-a4406430080b4f6d89adc14e9506e504
- 出典データセット
- uspto-grants-2016_03
- 特許番号
- US09290451B2
反応ノート
読み込み中…