HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-amino-2-methylpropanoate → 2-[(6-Cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridine-2-carbonyl)-amino]-2-methyl-propionic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-amino-2-methylpropanoate | HCID 4186341 | — |
| Reactant | 6-Cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridine-2-carboxylic acid | HCID 71087733 | — |
| Product | 2-[(6-Cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridine-2-carbonyl)-amino]-2-methyl-propionic acid methyl ester | HCID 71087291 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridine-2-carboxylic acid (Example 14 a) and 2-methyl-alanine methyl ester as starting materials, MS (LC/MS): 362.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-41ebe4d155234b6995311e876dc2ebad |
| Source note | uspto-grants-2016_03 |