HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Oxa-6-azaspiro[3.3]heptane → (6-Cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridin-2-yl)-(2-oxa-6-aza-spiro[3.3]hept-6-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Oxa-6-azaspiro[3.3]heptane | HCID 23111887 | — |
| Reactant | 6-Cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridine-2-carboxylic acid | HCID 71087733 | — |
| Product | (6-Cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridin-2-yl)-(2-oxa-6-aza-spiro[3.3]hept-6-yl)-methanone | HCID 71087919 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-pyrrolidin-1-yl-pyridine-2-carboxylic acid (Example 14 a) and 2-oxa-6-azaspiro[3.3]heptane (CAN 174-78-7) as starting materials, MS (EI): m/e=344.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-3f8272908eb44682853632c39da09fc0 |
| Source note | uspto-grants-2016_03 |