6-(3-Chlorophenyl)picolinic acid → HCID 71093616, compound

HRID 927420Notes

Reaction equation

HRID 927420 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[N:13]=[C:12]([C:14]([OH:16])=O)[CH:11]=[CH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1.[CH3:17][C:18]([CH3:26])([C:20]1[N:24]=[C:23]([CH3:25])[O:22][N:21]=1)[NH2:19]>>[CH3:17][C:18]([NH:19][C:14]([C:12]1[CH:11]=[CH:10][CH:9]=[C:8]([C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=2)[N:13]=1)=[O:16])([C:20]1[N:24]=[C:23]([CH3:25])[O:22][N:21]=1)[CH3:26]

Participants

3

Reactant 2

HCID 247301356-(3-Chlorophenyl)picolinic acidHCID 435592512-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-2-amine

Product 1

HCID 71093616HCID 71093616, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 6-(3-chlorophenyl)-2-pyridinecarboxylic acid (CAN 863704-38-5) and α,α,5-trimethyl-1,2,4-oxadiazole-3-methanamine (Example 33 d, CAN 1153831-97-0) as starting materials, MS (LC/MS): 357.1 [M+H]+.

Sources & evidence

ORD record
ord-bdb230b6b4884b7dac32ecfb768545d5
Source dataset
uspto-grants-2016_03
Patent number
US09290451B2

Reaction notes

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