2-(1,3-Thiazol-2-yl)propan-2-amine → HCID 71093543, compound

HRID 927424Notes

Reaction equation

HRID 927424 reaction equation
[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:15]([OH:17])=O)=[N:8][C:9]=2[O:10][CH2:11][CH:12]2[CH2:14][CH2:13]2)[CH2:3][CH2:2]1.[CH3:18][C:19]([CH3:26])([C:21]1[S:22][CH:23]=[CH:24][N:25]=1)[NH2:20]>>[CH3:18][C:19]([NH:20][C:15]([C:7]1[CH:6]=[CH:5][C:4]([CH:1]2[CH2:2][CH2:3]2)=[C:9]([O:10][CH2:11][CH:12]2[CH2:13][CH2:14]2)[N:8]=1)=[O:17])([C:21]1[S:22][CH:23]=[CH:24][N:25]=1)[CH3:26]

Participants

3

Reactant 2

HCID 282862032-(1,3-Thiazol-2-yl)propan-2-amineHCID 710873465-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid

Product 1

HCID 71093543HCID 71093543, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42 a) and α,α-dimethyl-2-thiazolemethanamine (CAN 1082393-38-1) as starting materials, MS (LC/MS): 358.1 [M+H]+.

Sources & evidence

ORD record
ord-13077ee65d8f43dea9afc16daa86dfcb
Source dataset
uspto-grants-2016_03
Patent number
US09290451B2

Reaction notes

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