HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(1,3-Thiazol-2-yl)propan-2-amine → 6-(3-Chloro-phenyl)-5-methyl-pyridine-2-carboxylic acid (1-methyl-1-thiazol-2-yl-ethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(1,3-Thiazol-2-yl)propan-2-amine | HCID 28286203 | — |
| Reactant | 6-(3-Chloro-phenyl)-5-methyl-pyridine-2-carboxylic acid | HCID 71087802 | — |
| Product | 6-(3-Chloro-phenyl)-5-methyl-pyridine-2-carboxylic acid (1-methyl-1-thiazol-2-yl-ethyl)-amide | HCID 71105565 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 6-(3-chloro-phenyl)-5-methyl-pyridine-2-carboxylic acid (Example 49 e) and α,α-dimethyl-2-thiazolemethanamine (CAN 1082393-38-1) as starting materials, MS (EI): 372.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-8bd38207008148c5827772abeb470f0d |
| Source note | uspto-grants-2016_03 |