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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927436Generated: October 27, 2026

2-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-2-amine → 6-(3-Chloro-phenyl)-5-methyl-pyridine-2-carboxylic acid [1-methyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethyl]-amide

https://huagongshe.com/reaction/927436

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-2-amineHCID 43559251—
Reactant6-(3-Chloro-phenyl)-5-methyl-pyridine-2-carboxylic acidHCID 71087802—
Product6-(3-Chloro-phenyl)-5-methyl-pyridine-2-carboxylic acid [1-methyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethyl]-amideHCID 71093621—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 6-(3-chloro-phenyl)-5-methyl-pyridine-2-carboxylic acid (Example 49 e) and α,α,5-trimethyl-1,2,4-oxadiazole-3-methanamine (CAN 1153831-97-0) as starting materials, MS (D): 371.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290451B2
Source datasetuspto-grants-2016_03
ORD IDord-2c53e576188f46e0b0cf4b08f8cc0f77
Source noteuspto-grants-2016_03