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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927440Generated: October 26, 2026

2-(1,3-Thiazol-2-yl)propan-2-amine → 5-Cyclopentyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (1-methyl-1-thiazol-2-yl-ethyl)-amide

https://huagongshe.com/reaction/927440

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(1,3-Thiazol-2-yl)propan-2-amineHCID 28286203—
Reactant5-Cyclopentyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 71087559—
Product5-Cyclopentyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (1-methyl-1-thiazol-2-yl-ethyl)-amideHCID 71093603—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-cyclopentyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 39 b) and α,α-dimethyl-2-thiazolemethanamine (CAN 1082393-38-1) as starting materials, MS (LC/MS): 386.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290451B2
Source datasetuspto-grants-2016_03
ORD IDord-3d1f6fbd0cb14c62919adaff4156c2bf
Source noteuspto-grants-2016_03