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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927445Generated: October 26, 2026

6-Cyclopropylmethoxy-5-methyl-pyridine-2-carboxylic acid → 6-Cyclopropylmethoxy-5-methyl-pyridine-2-carboxylic acid [(S)-2-cyclopropyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethyl]-amide

https://huagongshe.com/reaction/927445

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Cyclopropylmethoxy-5-methyl-pyridine-2-carboxylic acidHCID 71087599—
Reactant(S)-2-Cyclopropyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethylamineHCID 86674748—
Product6-Cyclopropylmethoxy-5-methyl-pyridine-2-carboxylic acid [(S)-2-cyclopropyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethyl]-amideHCID 71105568—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-methyl-pyridine-2-carboxylic acid (Example 36 d) and (S)-2-cyclopropyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethylamine (Example 38 e) as starting materials, MS (EI): m/e 357.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290451B2
Source datasetuspto-grants-2016_03
ORD IDord-b25c99291bd44e61867db560511770ac
Source noteuspto-grants-2016_03