Benzyl 2-(oxazol-2-yl)propan-2-ylcarbamate → 1-(4,5-Dihydro-oxazol-2-yl)-1-methyl-ethylamine

Participants

Reaction Steps

A mixture of benzyl 2-(oxazol-2-yl)propan-2-ylcarbamate (Example 8 d, 0.63 g) and palladium on carbon (10% w/w, 0.06 g) in ethanol (20 mL) was charged with hydrogen balloon and stirred at room temperature for 2 h. TLC showed the reaction was complete; it was filtered and concentrated to give the product as yellow oil (0.1 g, 33%); MS (EI): m/e=129.1 [M+H]+.

Provenance & Evidence