1-Aminopiperidine → HCID 71087578, compound

HRID 927460Notes

Reaction equation

HRID 927460 reaction equation
[CH:1]1([CH2:4][O:5][C:6]2[N:11]=[C:10]([C:12]([OH:14])=O)[CH:9]=[CH:8][CH:7]=2)[CH2:3][CH2:2]1.[N:15]1([NH2:21])[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1>>[N:15]1([NH:21][C:12]([C:10]2[CH:9]=[CH:8][CH:7]=[C:6]([O:5][CH2:4][CH:1]3[CH2:2][CH2:3]3)[N:11]=2)=[O:14])[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1

Participants

3

Reactant 2

HCID 166581-AminopiperidineHCID 50990528HCID 50990528, compound

Product 1

HCID 71087578HCID 71087578, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-pyridine-2-carboxylic acid (CAN 1248077-05-5) and 1-piperidinamine (CAN 2213-43-6) as starting materials, MS (LC/MS): 276.1 (M+H).

Sources & evidence

ORD record
ord-bded8bebb3a8437d94dadd58638f2712
Source dataset
uspto-grants-2016_03
Patent number
US09290451B2

Reaction notes

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