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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927475Generated: October 26, 2026

6-(4-Chlorophenyl)picolinic acid → 6-(4-Chloro-phenyl)-pyridine-2-carboxylic acid (1-ethyl-1-methylcarbamoyl-propyl)-amide

https://huagongshe.com/reaction/927475

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(4-Chlorophenyl)picolinic acidHCID 24730136—
Reactant2-Amino-2-ethyl-N-methyl-butyramideHCID 79810370—
Product6-(4-Chloro-phenyl)-pyridine-2-carboxylic acid (1-ethyl-1-methylcarbamoyl-propyl)-amideHCID 71093600—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 6-(4-chlorophenyl)-2-pyridinecarboxylic acid (CAN 135432-77-8) and 2-amino-2-ethyl-N-methyl-butyramide (Example 70 b) as starting materials, MS (EI): m/e=360.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290451B2
Source datasetuspto-grants-2016_03
ORD IDord-dbcdb735dfc248aea4e5d54b57176083
Source noteuspto-grants-2016_03