HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(1,3-Thiazol-2-yl)propan-2-amine → 6-(Cyclopropylmethoxy)-5-(1,1-dioxido-isothiazolidin-2-yl)-N-[2-(1,3-thiazol-2-yl)propan-2-yl]pyridine-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(1,3-Thiazol-2-yl)propan-2-amine | HCID 28286203 | — |
| Reactant | 6-Cyclopropylmethoxy-5-(1,1-dioxido-isothiazolidin-2-yl)-pyridine-2-carboxylic acid | HCID 71087711 | — |
| Product | 6-(Cyclopropylmethoxy)-5-(1,1-dioxido-isothiazolidin-2-yl)-N-[2-(1,3-thiazol-2-yl)propan-2-yl]pyridine-2-carboxamide | HCID 71087816 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-(1,1-dioxido-isothiazolidin-2-yl)-pyridine-2-carboxylic acid and α,α-dimethyl-2-thiazolemethanamine (CAN 1082393-38-1) as starting materials, MS (EI): m/e=437.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-4f9b176f79334387adddac9c508a2907 |
| Source note | uspto-grants-2016_03 |