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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 927481생성일: 2026년 10월 25일

6-Cyclopropylmethoxy-5-(3,3-difluoro-pyrrolidin-1-yl)-pyridine-2-carboxylic acid → 6-Cyclopropylmethoxy-5-(3,3-difluoro-pyrrolidin-1-yl)-pyridine-2-carboxylic acid (1-ethyl-1-methylcarbamoyl-propyl)-amide

https://huagongshe.com/reaction/927481

반응식

참여 물질

역할이름HCID투입량
반응물6-Cyclopropylmethoxy-5-(3,3-difluoro-pyrrolidin-1-yl)-pyridine-2-carboxylic acidHCID 71087750—
반응물2-Amino-2-ethyl-N-methyl-butyramideHCID 79810370—
생성물6-Cyclopropylmethoxy-5-(3,3-difluoro-pyrrolidin-1-yl)-pyridine-2-carboxylic acid (1-ethyl-1-methylcarbamoyl-propyl)-amideHCID 71093604—

반응 단계

The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-(3,3-difluoro-pyrrolidin-1-yl)-pyridine-2-carboxylic acid and 2-amino-2-ethyl-N-methyl-butyramide (Example 70 b) as starting materials, MS (EI): m/e=425.3 [M+H]+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09290451B2
출처 데이터셋uspto-grants-2016_03
ORD IDord-34ec03efefb44ecda668c36d57f5d92d
출처 메모uspto-grants-2016_03