HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(3-Chloro-phenyl)-5-cyclopropyl-pyridine-2-carboxylic acid → 6-(3-Chloro-phenyl)-5-cyclopropyl-pyridine-2-carboxylic acid (1-methyl-1-oxazol-2-yl-ethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(3-Chloro-phenyl)-5-cyclopropyl-pyridine-2-carboxylic acid | HCID 71087453 | — |
| Reactant | alpha,alpha-Dimethyl-2-oxazolemethanamine | HCID 82418817 | — |
| Product | 6-(3-Chloro-phenyl)-5-cyclopropyl-pyridine-2-carboxylic acid (1-methyl-1-oxazol-2-yl-ethyl)-amide | HCID 71093511 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 6-(3-chloro-phenyl)-5-cyclopropyl-pyridine-2-carboxylic acid (Example 48 e) and α,α-dimethyl-2-oxazolemethanamine (CAN 1211519-76-4) as starting materials, MS (EI): m/e=382.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-9f5f9cac5f7048c59b51c5e3eb71752c |
| Source note | uspto-grants-2016_03 |