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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927504Generated: October 25, 2026

(S)-alpha-amino-cyclopropanepropanamide → 5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid ((S)-1-carbamoyl-2-cyclopropyl-ethyl)-amide

https://huagongshe.com/reaction/927504

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-alpha-amino-cyclopropanepropanamideHCID 53964035—
Reactant5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 71087346—
Product5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid ((S)-1-carbamoyl-2-cyclopropyl-ethyl)-amideHCID 71105590—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42 a) and (S)-2-amino-3-cyclopropyl-propanamide (CAN 156077-93-9) as starting materials, MS (LC/MS): m/e=344.3 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290451B2
Source datasetuspto-grants-2016_03
ORD IDord-a61ac8bccdae475f9289af9521b73dab
Source noteuspto-grants-2016_03