HuagongsheHuagongshe Chemistry Print Report · For research reference only
Leucinamide → 5-Chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acid ((S)-1-carbamoyl-3-methyl-butyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Leucinamide | HCID 69640 | — |
| Reactant | 5-Chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acid | HCID 71087619 | — |
| Product | 5-Chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acid ((S)-1-carbamoyl-3-methyl-butyl)-amide | HCID 71105595 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 5-chloro-6-(3-chloro-phenyl)-pyridine-2-carboxylic acid (Example 58 c) and (2S)-2-amino-4-methyl-pentanamide (CAN 687-51-4) as starting materials, MS (EI): m/e=380.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-d65df0a5aedb4cc293419dba27d18f53 |
| Source note | uspto-grants-2016_03 |