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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927520Generated: October 26, 2026

(S)-alpha-amino-cyclopropanepropanamide → 5-Cyclopentyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid ((S)-1-carbamoyl-2-cyclopropyl-ethyl)-amide

https://huagongshe.com/reaction/927520

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-alpha-amino-cyclopropanepropanamideHCID 53964035—
Reactant5-Cyclopentyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 71087559—
Product5-Cyclopentyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid ((S)-1-carbamoyl-2-cyclopropyl-ethyl)-amideHCID 71105596—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-cyclopentyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 39 b) and (S)-2-amino-3-cyclopropyl-propionamide (CAN 156077-93-9) as starting materials, MS (EI): m/e=372.3 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290451B2
Source datasetuspto-grants-2016_03
ORD IDord-a2ab5b66738942d0a10be3f7c9e66e5b
Source noteuspto-grants-2016_03