HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-alpha-amino-cyclopropanepropanamide → 5-Bromo-6-cyclopropylmethoxy-pyridine-2-carboxylic acid ((S)-1-carbamoyl-2-cyclopropyl-ethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-alpha-amino-cyclopropanepropanamide | HCID 53964035 | — |
| Reactant | 5-Bromo-6-cyclopropylmethoxy-pyridine-2-carboxylic acid | HCID 71087543 | — |
| Product | 5-Bromo-6-cyclopropylmethoxy-pyridine-2-carboxylic acid ((S)-1-carbamoyl-2-cyclopropyl-ethyl)-amide | HCID 71105597 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 5-bromo-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 9 d) and (S)-2-amino-3-cyclopropyl-propionamide (CAN 156077-93-9) as starting materials, MS (EI): m/e=382.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-7e0fa0d83608452fa22b113f22a46841 |
| Source note | uspto-grants-2016_03 |