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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 927525생성일: 2026년 10월 25일

(S)-alpha-amino-cyclopropanepropanamide → 6-Cyclopropylmethoxy-5-(3,3-difluoro-pyrrolidin-1-yl)-pyridine-2-carboxylic acid ((S)-1-carbamoyl-2-cyclopropyl-ethyl)-amide

https://huagongshe.com/reaction/927525

반응식

참여 물질

역할이름HCID투입량
반응물(S)-alpha-amino-cyclopropanepropanamideHCID 53964035—
반응물6-Cyclopropylmethoxy-5-(3,3-difluoro-pyrrolidin-1-yl)-pyridine-2-carboxylic acidHCID 71087750—
생성물6-Cyclopropylmethoxy-5-(3,3-difluoro-pyrrolidin-1-yl)-pyridine-2-carboxylic acid ((S)-1-carbamoyl-2-cyclopropyl-ethyl)-amideHCID 71105598—

반응 단계

The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-(3,3-difluoro-pyrrolidin-1-yl)-pyridine-2-carboxylic acid (Example 78 b) and (S)-2-amino-3-cyclopropyl-propionamide (CAN 156077-93-9) as starting materials, MS (EI): m/e=409.3 [M+H]+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09290451B2
출처 데이터셋uspto-grants-2016_03
ORD IDord-4f4f0642ccac40c098981c43d25639a4
출처 메모uspto-grants-2016_03