HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acid → 6-Cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acid (1-methyl-1-oxazol-2-yl-ethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acid | HCID 71087457 | — |
| Reactant | alpha,alpha-Dimethyl-2-oxazolemethanamine | HCID 82418817 | — |
| Product | 6-Cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acid (1-methyl-1-oxazol-2-yl-ethyl)-amide | HCID 71105609 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acid (Example 113 d) and α,α-dimethyl-2-oxazolemethanamine (CAN 1211519-76-4) as starting materials, MS (EI): m/e=370.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-f3fe2a7d2c8149298b68d5e85830be81 |
| Source note | uspto-grants-2016_03 |