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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927555Generated: October 25, 2026

(S)-alpha-amino-cyclopropanepropanamide → 5-Cyclopropylamino-6-cyclopropylmethoxy-pyridine-2-carboxylic acid ((S)-1-carbamoyl-2-cyclopropyl-ethyl)-amide

https://huagongshe.com/reaction/927555

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-alpha-amino-cyclopropanepropanamideHCID 53964035—
Reactant5-Cyclopropylamino-6-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 71087191—
Product5-Cyclopropylamino-6-cyclopropylmethoxy-pyridine-2-carboxylic acid ((S)-1-carbamoyl-2-cyclopropyl-ethyl)-amideHCID 71105613—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-cyclopropylamino-6-cyclopropylmethoxy-pyridine-2-carboxylic acid and (S)-2-amino-3-cyclopropyl-propionamide (CAN 156077-93-9) as starting materials, MS (EI): m/e=359.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290451B2
Source datasetuspto-grants-2016_03
ORD IDord-184ae0d4ebe14ce9ae80284572f3b43a
Source noteuspto-grants-2016_03