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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927571Generated: October 26, 2026

Leucinamide → 5-Cyclopropyl-6-(2-methoxy-ethoxy)-pyridine-2-carboxylic acid ((S)-1-carbamoyl-3-methyl-butyl)-amide

https://huagongshe.com/reaction/927571

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLeucinamideHCID 69640—
Reactant5-Cyclopropyl-6-(2-methoxyethoxy)-pyridine-2-carboxylic acidHCID 71087473—
Product5-Cyclopropyl-6-(2-methoxy-ethoxy)-pyridine-2-carboxylic acid ((S)-1-carbamoyl-3-methyl-butyl)-amideHCID 71105622—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-(2-methoxy-ethoxy)-pyridine-2-carboxylic acid and (2S)-2-amino-4-methyl-pentanamide (CAN 687-51-4) as starting materials, MS (EI): m/e=350.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290451B2
Source datasetuspto-grants-2016_03
ORD IDord-e39a0afc9fd2447bbcd06f16a69c71e3
Source noteuspto-grants-2016_03