HCID 59511256, compound → 5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (1,1-dimethyl-3-morpholin-4-yl-propyl)-amide

HRID 927586Notes

Reaction equation

HRID 927586 reaction equation
[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:15]([OH:17])=O)=[N:8][C:9]=2[O:10][CH2:11][CH:12]2[CH2:14][CH2:13]2)[CH2:3][CH2:2]1.[CH3:18][C:19]([NH2:29])([CH3:28])[CH2:20][CH2:21][N:22]1[CH2:27][CH2:26][O:25][CH2:24][CH2:23]1>>[CH3:28][C:19]([NH:29][C:15]([C:7]1[CH:6]=[CH:5][C:4]([CH:1]2[CH2:2][CH2:3]2)=[C:9]([O:10][CH2:11][CH:12]2[CH2:13][CH2:14]2)[N:8]=1)=[O:17])([CH3:18])[CH2:20][CH2:21][N:22]1[CH2:23][CH2:24][O:25][CH2:26][CH2:27]1

Participants

3

Reactant 2

HCID 59511256HCID 59511256, compoundHCID 710873465-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid

Product 1

HCID 711056295-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (1,1-dimethyl-3-morpholin-4-yl-propyl)-amide

Procedure

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42 a) and 1,1-dimethyl-3-morpholin-4-yl-propylamine (Example 35 d) as starting materials, MS (EI): m/e=388.3 [M+H]+.

Sources & evidence

ORD record
ord-9f3a01cc6f3e4d58a8210d6e826f4bd3
Source dataset
uspto-grants-2016_03
Patent number
US09290451B2

Reaction notes

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