Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927601Generated: October 26, 2026

2-Amino-2-methyl-1-propanol → 5-Cyclopropylamino-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide

https://huagongshe.com/reaction/927601

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-2-methyl-1-propanolHCID 11807—
Reactant5-Cyclopropylamino-6-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 71087191—
Product5-Cyclopropylamino-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (2-hydroxy-1,1-dimethyl-ethyl)-amideHCID 71105634—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-cyclopropylamino-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 133 b) and 2-amino-2-methyl-1-propanol (CAN 124-68-5) as starting materials, MS (EI): m/e=401.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290451B2
Source datasetuspto-grants-2016_03
ORD IDord-2a81c45b31794bae848fedde988a4852
Source noteuspto-grants-2016_03