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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927614Generated: October 26, 2026

2-Amino-2-methylpropionitrile → N-(2-Cyanopropan-2-yl)-5-cyclopropyl-6-(cyclopropylmethoxy)picolinamide

https://huagongshe.com/reaction/927614

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-2-methylpropionitrileHCID 88022—
Reactant5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 71087346—
ProductN-(2-Cyanopropan-2-yl)-5-cyclopropyl-6-(cyclopropylmethoxy)picolinamideHCID 71087913—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42 a) and 2-amino-2-methyl-propanenitrile, (CAN 19355-69-2) as starting materials, LC-MS (UV peak area/ESI) 89%, 300.1702 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290451B2
Source datasetuspto-grants-2016_03
ORD IDord-66c429e0ae634cb2823a4a73dcc4831b
Source noteuspto-grants-2016_03