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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927622Generated: October 25, 2026

1-Aminocyclopentanemethanol → 5-Cyclopropyl-6-(cyclopropylmethoxy)-N-(1-(hydroxymethyl)cyclopentyl)picolinamide

https://huagongshe.com/reaction/927622

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-AminocyclopentanemethanolHCID 66307—
Reactant5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 71087346—
Product5-Cyclopropyl-6-(cyclopropylmethoxy)-N-(1-(hydroxymethyl)cyclopentyl)picolinamideHCID 71087511—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42 a) and 1-amino-cyclopentanemethanol (CAN 10316-79-7) as starting materials, LC-MS (UV peak area/ESI) 100%, 331.2014 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290451B2
Source datasetuspto-grants-2016_03
ORD IDord-48c3998dab4c4967a0c67c488a131d16
Source noteuspto-grants-2016_03