Leucinamide → HCID 86674776, compound
Reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:9]([OH:11])=O)=[N:6][C:7]=1[Cl:8].[NH2:12][C@@H:13]([CH2:17][CH:18]([CH3:20])[CH3:19])[C:14]([NH2:16])=[O:15]>>[C:14]([C@@H:13]([NH:12][C:9]([C:5]1[CH:4]=[CH:3][C:2]([Br:1])=[C:7]([Cl:8])[N:6]=1)=[O:11])[CH2:17][CH:18]([CH3:20])[CH3:19])(=[O:15])[NH2:16]Participants
3
Procedure
The title compound was synthesized in analogy to Example 1, using 5-bromo-6-chloropicolinic acid (CAN 959958-25-9) and (2S)-2-amino-4-methyl-pentanamide (CAN 687-51-4) as starting materials, MS (EI): m/e=350.0 [M+H]+.
Sources & evidence
- ORD record
- ord-a1b72acdf7ec422ebd583dabf33335d8
- Source dataset
- uspto-grants-2016_03
- Patent number
- US09290451B2
Reaction notes
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