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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927626Generated: October 26, 2026

2-Amino-3,3-dimethylbutanamide hydrochloride → N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-5-cyclopropyl-6-(cyclopropylmethoxy)picolinamide

https://huagongshe.com/reaction/927626

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-3,3-dimethylbutanamide hydrochlorideHCID 50988058—
Reactant5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 71087346—
ProductN-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-5-cyclopropyl-6-(cyclopropylmethoxy)picolinamideHCID 71087686—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42 a) and 2-amino-3,3-dimethyl-butanamide hydrochloride (1:1) (CAN 359844-68-1) as starting materials, LC-MS (UV peak area/ESI) 100%, 346.2113 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290451B2
Source datasetuspto-grants-2016_03
ORD IDord-d8430171537842de9bd9f3feb892a235
Source noteuspto-grants-2016_03