4-Amino-tetrahydro-2H-pyran-4-carboxamide → HCID 71105641, compound

HRID 927627Notes

Reaction equation

HRID 927627 reaction equation
[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:15]([OH:17])=O)=[N:8][C:9]=2[O:10][CH2:11][CH:12]2[CH2:14][CH2:13]2)[CH2:3][CH2:2]1.[NH2:18][C:19]1([C:25]([NH2:27])=[O:26])[CH2:24][CH2:23][O:22][CH2:21][CH2:20]1>>[C:25]([C:19]1([NH:18][C:15]([C:7]2[CH:6]=[CH:5][C:4]([CH:1]3[CH2:2][CH2:3]3)=[C:9]([O:10][CH2:11][CH:12]3[CH2:13][CH2:14]3)[N:8]=2)=[O:17])[CH2:24][CH2:23][O:22][CH2:21][CH2:20]1)(=[O:26])[NH2:27]

Participants

3

Reactant 2

HCID 509895814-Amino-tetrahydro-2H-pyran-4-carboxamideHCID 710873465-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid

Product 1

HCID 71105641HCID 71105641, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42 a) and 4-aminotetrahydro-2H-pyran-4-carboxamide (CAN 1183378-09-7) as starting materials, MS (EI): m/e=360.1 [M+H]+.

Sources & evidence

ORD record
ord-03d410a8ab09437882bb81de9761953b
Source dataset
uspto-grants-2016_03
Patent number
US09290451B2

Reaction notes

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