HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(5-Methyl-1,2,4-oxadiazol-3-yl)cyclobutan-1-amine hydrochloride → 5-Cyclopropyl-N-(1-(5-methyl-1,2,4-oxadiazol-3-yl)cyclobutyl)-6-(pyridin-2-ylmethoxy)picolinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(5-Methyl-1,2,4-oxadiazol-3-yl)cyclobutan-1-amine hydrochloride | HCID 42959052 | — |
| Reactant | 5-Cyclopropyl-6-(pyridin-2-ylmethoxy)-pyridine-2-carboxylic acid | HCID 71087785 | — |
| Product | 5-Cyclopropyl-N-(1-(5-methyl-1,2,4-oxadiazol-3-yl)cyclobutyl)-6-(pyridin-2-ylmethoxy)picolinamide | HCID 71087636 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-(pyridin-2-ylmethoxy)-pyridine-2-carboxylic acid and 1-(5-methyl-1,2,4-oxadiazol-3-yl)-cyclobutanamine hydrochloride (1:1) (CAN 1170897-28-5) as starting materials, MS (EI): m/e=406.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-b7d1e7b9076546689b671b871f59f6eb |
| Source note | uspto-grants-2016_03 |