HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-2-Amino-N,3,3-trimethylbutanamide → (S)-5-Cyclopropyl-N-(3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-6-(pyridin-2-ylmethoxy)picolinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-2-Amino-N,3,3-trimethylbutanamide | HCID 445856 | — |
| Reactant | 5-Cyclopropyl-6-(pyridin-2-ylmethoxy)-pyridine-2-carboxylic acid | HCID 71087785 | — |
| Product | (S)-5-Cyclopropyl-N-(3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-6-(pyridin-2-ylmethoxy)picolinamide | HCID 71087804 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-(pyridin-2-ylmethoxy)-pyridine-2-carboxylic acid (Example 189 b) and (2S)-2-amino-N,3,3-trimethyl-butanamide (CAN 89226-12-0) as starting materials, MS (EI): m/e=397.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-f6a7dfdeb47c4f11989eeb93a85910a4 |
| Source note | uspto-grants-2016_03 |