HRID927652

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2758247

3,3-Difluoroazetidine hydrochloride

C3H6ClF2N

结构：CNC(=O)[C@@H](NC(=O)c1ccc(Br)c(OCC2CCCO2)n1)C(C)(C)C

HCID71105644

未命名化合物

PRODUCTS

生成物

结构：CNC(=O)[C@@H](NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CCCO2)n1)C(C)(C)C

HCID71088005

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized by addition of 3,3-difluoroazetidine hydrochloride (CAN 288315-03-7) to 5-bromo-6-(tetrahydro-furan-2-ylmethoxy)-pyridine-2-carboxylic acid ((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-amide (Example 188) in analogy to the procedure described in Example 69 a, MS (EI): m/e=441.0 [M+H]+.