HCID 26249012, compound → HCID 71087851, compound

HRID 927656Notes

Reaction equation

HRID 927656 reaction equation
[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:15]([OH:17])=O)=[N:8][C:9]=2[O:10][CH2:11][CH:12]2[CH2:14][CH2:13]2)[CH2:3][CH2:2]1.[F:18][C:19]([F:29])([F:28])[C@@H:20]([NH2:27])[C:21]1[CH:22]=[N:23][CH:24]=[CH:25][CH:26]=1>>[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:15]([NH:27][C@@H:20]([C:21]3[CH:22]=[N:23][CH:24]=[CH:25][CH:26]=3)[C:19]([F:18])([F:28])[F:29])=[O:17])=[N:8][C:9]=2[O:10][CH2:11][CH:12]2[CH2:13][CH2:14]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 26249012HCID 26249012, compoundHCID 710873465-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid

Product 1

HCID 71087851HCID 71087851, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42 a) and (S)-2,2,2-trifluoro-1-pyridin-3-yl-ethylamine (CAN 336105-46-5) as starting materials, MS (EI): m/e=392.2 [M+H]+.

Sources & evidence

ORD record
ord-5091a7eeff0f48088ea9f1231349af6a
Source dataset
uspto-grants-2016_03
Patent number
US09290451B2

Reaction notes

Loading…