HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid → 5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid ((S)-2-cyclopropyl-1-dimethylcarbamoyl-ethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid | HCID 71087346 | — |
| Reactant | (S)-2-Amino-3-cyclopropyl-N,N-dimethylpropanamide hydrochloride | HCID 86674779 | — |
| Product | 5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid ((S)-2-cyclopropyl-1-dimethylcarbamoyl-ethyl)-amide | HCID 71105653 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethyloxy-pyridine-2-carboxylic acid (Example 42 a) and (S)-2-amino-3-cyclopropyl-N,N-dimethylpropanamide hydrochloride as starting materials, LC-MS (UV peak area/ESI) 100%, 372.2278 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-1540a633029e4a53a071d2b8d8f45072 |
| Source note | uspto-grants-2016_03 |