HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-2-amino-N,4,4-trimethyl-pentanamide → 6-Cyclopropylmethoxy-5-(6-oxa-1-aza-spiro[3.3]hept-1-yl)-pyridine-2-carboxylic acid ((S)-3,3-dimethyl-1-methylcarbamoyl-butyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-2-amino-N,4,4-trimethyl-pentanamide | HCID 57635521 | — |
| Reactant | 6-(Cyclopropylmethoxy)-5-(6-oxa-1-azaspiro[3.3]heptan-1-yl)picolinic acid | HCID 71087704 | — |
| Product | 6-Cyclopropylmethoxy-5-(6-oxa-1-aza-spiro[3.3]hept-1-yl)-pyridine-2-carboxylic acid ((S)-3,3-dimethyl-1-methylcarbamoyl-butyl)-amide | HCID 71113055 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 6-(cyclopropylmethoxy)-5-(6-oxa-1-azaspiro[3.3]heptan-1-yl)picolinic acid and (2S)-2-amino-N,4,4-trimethyl-pentanamide (CAN 1160161-70-5) as starting materials. MS (EI): m/e=431.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-c6a2a97eaca14b02aa0653265b904307 |
| Source note | uspto-grants-2016_03 |