HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acid → 2-[(6-Cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carbonyl)-amino]-2-ethyl-butyric acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acid | HCID 71087457 | — |
| Reactant | Methyl 2-amino-2-ethylbutanoate hydrochloride | HCID 75488114 | — |
| Product | 2-[(6-Cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carbonyl)-amino]-2-ethyl-butyric acid methyl ester | HCID 71087209 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acid (Example 113 d) and methyl 2-amino-2-ethylbutanoate hydrochloride (CAN 92398-54-4) as starting materials. MS (EI): m/e=389.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-649bab93c96a47a1b6c8ac97cd8773a4 |
| Source note | uspto-grants-2016_03 |