Methylamine hydrochloride → HCID 71113056, compound

HRID 927693Notes

Reaction equation

[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:17]([NH:19][C:20]([CH2:26][CH3:27])([CH2:24][CH3:25])[C:21](O)=[O:22])=[O:18])=[N:8][C:9]=2[O:10][CH2:11][CH:12]2[CH2:16][CH2:15][CH2:14][O:13]2)[CH2:3][CH2:2]1.Cl.[CH3:29][NH2:30]>>[CH2:24]([C:20]([NH:19][C:17]([C:7]1[CH:6]=[CH:5][C:4]([CH:1]2[CH2:2][CH2:3]2)=[C:9]([O:10][CH2:11][CH:12]2[CH2:16][CH2:15][CH2:14][O:13]2)[N:8]=1)=[O:18])([C:21](=[O:22])[NH:30][CH3:29])[CH2:26][CH3:27])[CH3:25]

Participants

Reactant 2

HCID 6364545Methylamine hydrochloride

HCID 710876312-(5-Cyclopropyl-6-((tetrahydrofuran-2-yl)methoxy)picolinamido)-2-ethylbutanoic acid

Product 1

HCID 71113056HCID 71113056, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 2-(5-cyclopropyl-6-((tetrahydrofuran-2-yl)methoxy)picolinamido)-2-ethylbutanoic acid and methanamine hydrochloride as starting materials, MS (EI): m/e=390.3 [M+H]+.

Sources & evidence

ORD record: ord-f0203b35f05445c3bf0aa9bb327570e3
Source dataset: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09290451B2

Reaction notes

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