HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-amino-2-ethylbutanoate hydrochloride → Ethyl 2-(6-(cyclopropylmethoxy)-5-(trifluoromethyl)picolinamido)-2-ethylbutanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-amino-2-ethylbutanoate hydrochloride | HCID 24201639 | — |
| Reactant | 6-Cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acid | HCID 71087457 | — |
| Product | Ethyl 2-(6-(cyclopropylmethoxy)-5-(trifluoromethyl)picolinamido)-2-ethylbutanoate | HCID 71087413 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acid (Example 113 d) and ethyl 2-amino-2-ethylbutanoate hydrochloride (CAN 1135219-29-2) as starting materials, MS (EI): m/e=403.4 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-f73b2458ff184fb7bf259a04e47297cd |
| Source note | uspto-grants-2016_03 |