HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-amino-2-ethylbutanoate hydrochloride → 2-Ethyl-2-{[6-(tetrahydro-furan-2-ylmethoxy)-5-trifluoromethyl-pyridine-2-carbonyl]-amino}-butyric acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-amino-2-ethylbutanoate hydrochloride | HCID 24201639 | — |
| Reactant | 6-((Tetrahydrofuran-2-yl)methoxy)-5-(trifluoromethyl)picolinic acid | HCID 71087646 | — |
| Product | 2-Ethyl-2-{[6-(tetrahydro-furan-2-ylmethoxy)-5-trifluoromethyl-pyridine-2-carbonyl]-amino}-butyric acid ethyl ester | HCID 71087782 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 6-((tetrahydrofuran-2-yl)methoxy)-5-(trifluoromethyl)picolinic acid and ethyl 2-amino-2-ethylbutanoate hydrochloride (CAN 1135219-29-2) as starting materials. MS (EI): m/e=433.4 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-c6eadb1cdda84f2b92bdfa2024552ed6 |
| Source note | uspto-grants-2016_03 |