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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927707Generated: October 25, 2026

Ethyl 2-amino-2-ethylbutanoate hydrochloride → 2-[(5-Bromo-6-cyclopropylmethoxy-pyridine-2-carbonyl)-amino]-2-ethyl-butyric acid ethyl ester

https://huagongshe.com/reaction/927707

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-amino-2-ethylbutanoate hydrochlorideHCID 24201639—
Reactant5-Bromo-6-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 71087543—
Product2-[(5-Bromo-6-cyclopropylmethoxy-pyridine-2-carbonyl)-amino]-2-ethyl-butyric acid ethyl esterHCID 71087280—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-bromo-6-(cyclopropylmethoxy)-pyridine-2-carboxylic acid (Example 9 d) and ethyl 2-amino-2-ethylbutanoate hydrochloride (CAN 1135219-29-2) as starting materials. MS (EI): m/e=415.0 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290451B2
Source datasetuspto-grants-2016_03
ORD IDord-f8fe5b9748eb425cb9f668745c625566
Source noteuspto-grants-2016_03